Owen A M, Stern C E, Look R B, Tracey I, Rosen B R, Petrides M
Medical Research Council Applied Psychology Unit, 15 Chaucer Road, Cambridge, CB2 2EF, United Kingdom.
Proc Natl Acad Sci U S A. 1998 Jun 23;95(13):7721-6. doi: 10.1073/pnas.95.13.7721.
The present study used functional magnetic resonance imaging to demonstrate that performance of visual spatial and visual nonspatial working memory tasks involve the same regions of the lateral prefrontal cortex when all factors unrelated to the type of stimulus material are appropriately controlled. These results provide evidence that spatial and nonspatial working memory may not be mediated, respectively, by mid-dorsolateral and mid-ventrolateral regions of the frontal lobe, as widely assumed, and support the alternative notion that specific regions of the lateral prefrontal cortex make identical executive functional contributions to both spatial and nonspatial working memory.
本研究使用功能磁共振成像来证明,当与刺激材料类型无关的所有因素得到适当控制时,视觉空间和视觉非空间工作记忆任务的执行涉及外侧前额叶皮质的相同区域。这些结果提供了证据,表明空间和非空间工作记忆可能并非如广泛假设的那样,分别由额叶的背外侧中部和腹外侧中部区域介导,并支持了另一种观点,即外侧前额叶皮质的特定区域对空间和非空间工作记忆做出相同的执行功能贡献。