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白塞病的关节表现。340例病例回顾。

Joint manifestations in Behçet's disease. A review of 340 cases.

作者信息

Benamour S, Zeroual B, Alaoui F Z

机构信息

Department of Internal Medicine, Inb Rochd University Hospital, Casablanca, Morocco.

出版信息

Rev Rhum Engl Ed. 1998 May;65(5):299-307.

PMID:9636948
Abstract

OBJECTIVES

To gain additional knowledge on the joint manifestations of Behçet's disease, with special attention to unusual forms.

PATIENTS AND METHODS

Retrospective review of 340 cases with joint manifestations identified among 601 cases of Behçet's disease seen over a 15-year period. All the patients met International Study Group for Behçet's disease criteria. Radiographs of all joints with arthritis were obtained. Starting ten years ago, a radiograph of the sacroiliac joint was taken routinely.

RESULTS

Joint manifestations were present in more than half the patients (56.57%) and were inaugural in 18.23% of cases. The knees and ankles were the joints most commonly affected. Monoarthritis and oligoarthritis were seen in 16.17% and 11.76% of cases, respectively and polyarthritis involving the large limb joints and the small joints of the hands and feet in 17.05% of cases. Unusual forms included polyarthritis with deformities and/or destruction (n: 8, including two patients who also met criteria for rheumatoid arthritis), pseudogout (n: 5), popliteal cyst (n: 3, including one case imitating deep vein thrombosis), myositis (n: 1), spondylarthropathy (n: 5), and Sjögren's syndrome (n: 2). Children were more likely than adults to have joint manifestations (73.68%) and polyarthritis (35.7%).

CONCLUSION

Joint manifestations are common in Behçet's disease. Their unusual forms deserve to be known since they can raise diagnostic problems when they are inaugural.

摘要

目的

获取有关白塞病关节表现的更多知识,尤其关注不寻常形式。

患者与方法

回顾性分析15年间601例白塞病患者中确诊的340例有关节表现的病例。所有患者均符合白塞病国际研究组的标准。对所有患有关节炎的关节进行了X线摄片。从十年前开始,常规拍摄骶髂关节的X线片。

结果

超过半数患者(56.57%)存在关节表现,其中18.23%的病例以关节表现为首发症状。膝关节和踝关节是最常受累的关节。单关节炎和少关节炎分别见于16.17%和11.76%的病例,17.05%的病例为累及大肢体关节及手足小关节的多关节炎。不寻常形式包括伴有畸形和/或破坏的多关节炎(8例,包括2例也符合类风湿关节炎标准的患者)、假性痛风(5例)、腘窝囊肿(3例,包括1例疑似深静脉血栓形成的病例)、肌炎(1例)、脊柱关节病(5例)和干燥综合征(2例)。儿童比成人更易出现关节表现(73.68%)和多关节炎(35.7%)。

结论

关节表现在白塞病中很常见。其不寻常形式值得关注,因为首发时可能会引发诊断问题。

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1
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Rev Rhum Engl Ed. 1998 May;65(5):299-307.
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