Jaffrain-Rea M L, Minniti G, Santoro A, Bastianello S, Tamburrano G, Gulino A, Cantore G
Dipartimento di Medicina Sperimentale, Università degli Studi, L'Aquila (AQ), Italy.
Clin Neurol Neurosurg. 1998 Mar;100(1):40-3. doi: 10.1016/s0303-8467(97)00110-8.
Meningiomas of the tuberculum sellae can induce compression of the optic tract. We report the case of a 54-year-old female patient affected by a suspected pituitary macroadenoma with severe visual field defects, who experienced a significant clinical and visual improvement during short-term octreotide therapy, contrasting with the lack of neuroradiological evidence for tumor shrinkage. The patient subsequently underwent transcranial surgery with a final diagnosis of meningioma. The putative mechanisms of visual improvement during octreotide therapy are discussed.
