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Visual improvement during octreotide therapy in a case of episellar meningioma.

作者信息

Jaffrain-Rea M L, Minniti G, Santoro A, Bastianello S, Tamburrano G, Gulino A, Cantore G

机构信息

Dipartimento di Medicina Sperimentale, Università degli Studi, L'Aquila (AQ), Italy.

出版信息

Clin Neurol Neurosurg. 1998 Mar;100(1):40-3. doi: 10.1016/s0303-8467(97)00110-8.

Abstract

Meningiomas of the tuberculum sellae can induce compression of the optic tract. We report the case of a 54-year-old female patient affected by a suspected pituitary macroadenoma with severe visual field defects, who experienced a significant clinical and visual improvement during short-term octreotide therapy, contrasting with the lack of neuroradiological evidence for tumor shrinkage. The patient subsequently underwent transcranial surgery with a final diagnosis of meningioma. The putative mechanisms of visual improvement during octreotide therapy are discussed.

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