Cocanour C S, Moore F A, Ware D N, Marvin R G, Clark J M, Duke J H
University of Texas-Houston Medical School, USA.
Arch Surg. 1998 Jun;133(6):619-24; discussion 624-5. doi: 10.1001/archsurg.133.6.619.
To determine the incidence and type of delayed complications from nonoperative management of adult splenic injury.
Retrospective medical record review.
University teaching hospital, level I trauma center.
Two hundred eighty patients were admitted to the adult trauma service with blunt splenic injury during a 4-year period. Men constituted 66% of the population. The mean (+/-SEM) age was 32.2+/-1.0 years and the mean (+/-SEM) Injury Severity Score was 22.8+/-0.9. Fifty-nine patients (21%) died of multiple injuries within 48 hours and were eliminated from the study. One hundred thirty-four patients (48%) were treated operatively within the first 48 hours after injury and 87 patients (31%) were managed nonoperatively.
We reviewed the number of units of blood transfused, intensive care unit length of stay, overall length of stay, outcome, and complications occurring more than 48 hours after injury directly attributable to the splenic injury.
Patients managed nonoperatively had a significantly lower Injury Severity Score (P<.05) than patients treated operatively. Length of stay was significantly decreased in both the number of intensive care unit days as well as total length of stay (P<.05). The number of units of blood transfused was also significantly decreased in patients managed nonoperatively (P<.05). Seven patients (8%) managed nonoperatively developed delayed complications requiring intervention. Five patients had overt bleeding that occurred at 4 days (3 patients), 6 days (1 patient), and 8 days (1 patient) after injury. Three patients underwent splenectomy, 1 had a splenic artery pseudoaneurysm embolization, and 1 had 2 areas of bleeding embolization. Two patients developed splenic abscesses at approximately 1 month after injury; both were treated by splenectomy.
Significant numbers of delayed splenic complications do occur with nonoperative management of splenic injuries and are potentially life-threatening.
确定成人脾损伤非手术治疗后延迟并发症的发生率及类型。
回顾性病历审查。
大学教学医院,一级创伤中心。
在4年期间,280例成年创伤患者因钝性脾损伤入住成人创伤科。男性占66%。平均(±标准误)年龄为32.2±1.0岁,平均(±标准误)损伤严重度评分(ISS)为22.8±0.9。59例患者(21%)在48小时内死于多发伤,被排除在研究之外。134例患者(48%)在受伤后48小时内接受了手术治疗,87例患者(31%)接受了非手术治疗。
我们回顾了输血单位数、重症监护病房住院时间、总住院时间、结局以及受伤48小时后直接归因于脾损伤的并发症。
非手术治疗的患者损伤严重度评分显著低于手术治疗的患者(P<0.05)。重症监护病房天数和总住院时间均显著缩短(P<0.05)。非手术治疗的患者输血量也显著减少(P<0.05)。7例(8%)接受非手术治疗的患者出现了需要干预的延迟并发症。5例患者出现明显出血,分别发生在受伤后4天(3例)、6天(1例)和8天(1例)。3例患者接受了脾切除术,1例进行了脾动脉假性动脉瘤栓塞术,1例对2处出血部位进行了栓塞术。2例患者在受伤后约1个月出现脾脓肿;均接受了脾切除术。
脾损伤非手术治疗确实会出现大量延迟性脾并发症,且可能危及生命。