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[胸膜孤立性纤维瘤术后20年出现恶性复发:再次切除的病例报告]

[Malignant recurrence of solitary fibrous tumor of the pleura developed 20 years after the surgery: a case report of re-extirpation].

作者信息

Ito H, Arai T, Niino H, Inagaki K, Morita T, Yano M, Nomura T

机构信息

Department of Thoracic Surgery, International Medical Center of Japan, Tokyo, Japan.

出版信息

Kyobu Geka. 1998 Jun;51(6):504-7.

PMID:9637847
Abstract

A 63-year-old female developed the chest wall tumor protruding into the right thoracic cavity. She consulted our hospital complaining of chest pain. 20 years before this episode, she had undergone tumor extirpation combined with the partial resection of adherent anterior chest wall and the diaphragm for large benign solitary fibrous tumor of the pleura. Because of the difficulty in making diagnosis by needle biopsy, operation (re-tumor extirpation combined with the chest wall) was done. Histological examination revealed that the tumor was malignant solitary fibrous tumor. We concluded that the tumor was the malignant recurrence of the benign solitary fibrous tumor resected 20 years before. Occasionally, benign solitary fibrous tumor of the pleura recurs and behaves more aggressively than primary, but such a long latent period as 20 years is quite uncommon. So we present the case and the review of the literature.

摘要

一名63岁女性出现突入右胸腔的胸壁肿瘤。她因胸痛前来我院就诊。此次发病20年前,她曾因胸膜巨大良性孤立性纤维瘤接受肿瘤切除,同时行粘连的前胸壁和膈肌部分切除术。由于针吸活检难以确诊,遂进行了手术(再次肿瘤切除并胸壁手术)。组织学检查显示该肿瘤为恶性孤立性纤维瘤。我们得出结论,该肿瘤是20年前切除的良性孤立性纤维瘤发生了恶性复发。偶尔,胸膜良性孤立性纤维瘤会复发,且比原发肿瘤表现得更具侵袭性,但长达20年的如此长潜伏期相当罕见。因此,我们呈现此病例并进行文献复习。

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