血液透析患者丙型肝炎病毒基因型的转变
Turnover of hepatitis C virus genotypes in hemodialysis patients.
作者信息
Pujol F H, Devesa M, Loureiro C L, Capriles F, Liprandi F
机构信息
Laboratorio de Biología de Virus, CMBC, IVIC, Caracas, Venezuela.
出版信息
Arch Virol. 1998;143(4):823-7. doi: 10.1007/s007050050334.
PMID:9638152
Abstract
Hepatitis C virus (HCV) genotypes were determined in hemodialysis patients with a high prevalence and incidence of infection. A change of HCV genotype was observed in 6/14 follow-up samples analyzed 13 and 21 months later. The appearance and disappearance of HCV genotypes may be due to either genotype-specific intermittent viremic status or viral interference.
摘要
在感染率和发病率较高的血液透析患者中确定了丙型肝炎病毒（HCV）基因型。在13个月和21个月后分析的14份随访样本中的6份中观察到HCV基因型的变化。HCV基因型的出现和消失可能是由于基因型特异性间歇性病毒血症状态或病毒干扰。
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