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可实现的实验室标准;对99例宫颈癌患者的细胞学检查回顾

Achievable laboratory standards; a review of cytology of 99 women with cervical cancer.

作者信息

Womack C, Warren A Y

机构信息

Department of Histopathology and Cytopathology, Peterborough District Hospital, UK.

出版信息

Cytopathology. 1998 Jun;9(3):171-7. doi: 10.1046/j.1365-2303.1998.00122.x.

DOI:10.1046/j.1365-2303.1998.00122.x
PMID:9638378
Abstract

The Working Party guidelines are a significant advance in the audit of the National Health Service Cervical Screening Programme (NHSCSP), the priority of which is to reduce mortality and morbidity from cervical cancer. This study was undertaken to apply the guidance on review of screening history to a series of 99 women with invasive cervical cancer diagnosed in one centre during a 9 year period. The majority (approx. 64%) of these women had not been screened within the 5 years preceding diagnosis, 25% had negative, inadequate or abnormal smears and 6% had previous treatment for cervical intraepithelial neoplasia (CIN). In four patients diagnosis was delayed. No standards are yet available to test the results of this series of women. Cervical cancer is relatively uncommon, and for data to be aggregated and compared across the UK, it is important that strict criteria are developed and applied to ensure that recruitment to the Working Party categories is uniform and not open to local interpretation. Full review and documentation of screening history should be mandatory for all women who develop cervical cancer.

摘要

工作小组指南是国民医疗服务体系宫颈筛查计划(NHSCSP)审计工作的一项重大进展,该计划的首要任务是降低宫颈癌的死亡率和发病率。本研究旨在将筛查史审查指南应用于9年间在一个中心诊断出的99例浸润性宫颈癌女性患者。这些女性中,大多数(约64%)在诊断前5年内未接受过筛查,25%的涂片检查结果为阴性、不充分或异常,6%曾接受过宫颈上皮内瘤变(CIN)治疗。4例患者的诊断被延误。目前尚无标准可用于检验这组女性患者的结果。宫颈癌相对不常见,为了在全英国汇总和比较数据,制定并应用严格标准非常重要,以确保纳入工作小组类别的标准统一,不受地方解释的影响。对于所有患宫颈癌的女性,应强制进行全面的筛查史审查和记录。

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引用本文的文献

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Cervical cancer screening history prior to a diagnosis of cervical cancer in Danish women aged 60 years and older-A national cohort study.丹麦 60 岁及以上女性宫颈癌诊断前的宫颈癌筛查史:一项全国队列研究。
Cancer Med. 2019 Jan;8(1):418-427. doi: 10.1002/cam4.1926. Epub 2019 Jan 1.
2
How can we develop a cost-effective quality cervical screening programme?我们如何制定一个具有成本效益的高质量宫颈癌筛查计划?
Br J Gen Pract. 2002 Jun;52(479):485-90.