Damiani P C, Bearzotti M, Cabezón M, Olivieri A C
Departamento de Química Analítica, Facultad de Ciencias Bioquímicas y Farmacéuticas, Universidad Nacional de Rosario, Argentina.
J Pharm Biomed Anal. 1998 Jun;17(2):233-6. doi: 10.1016/s0731-7085(97)00166-0.
The spectrofluorometric determination of piroxicam [4-hydroxy-2-methyl-N-(2-pyridyl)-2II-1,2-benzothiazine-3-carboxam ide-1, 1-dioxide] in pharmaceutical tablets is described. It involves excitation at 330 nm of an acid solution (HNO3 0.5 M) of the drug, and measurement of the fluorescence intensity at 440 nm. The linear range is 0.01-1.25 micrograms ml-1.
