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肠炎沙门氏菌中的噬菌体限制作用和小质粒的存在

Phage restriction and the presence of small plasmids in Salmonella enteritidis.

作者信息

Gadó I, László V G, Nagy B, Milch H, Drin I, Awad-Masalmeh M, Horváth J

机构信息

Phage Department, B. Johan National Institute of Public Health, Budapest, Hungary.

出版信息

Zentralbl Bakteriol. 1998 May;287(4):509-19. doi: 10.1016/s0934-8840(98)80192-8.

DOI:10.1016/s0934-8840(98)80192-8
PMID:9638880
Abstract

Between 1990-1994, a total of 16,505 S. enteritidis strains of human, animal and food origin were phage-typed, using the Hungarian scheme and the changes of incidence of the dominant phage types were monitored. The incidence of PT1 (corresponding to Ward's PT1 was very high between 1990 and 1992 (67.9-71.0% of the total S. enteritidis isolates), later, it decreased. The prevalence of PT6 (corresponding to Ward's PT4) was rare until 1992, then it gradually increased. The phage type and plasmid content of 78 Salmonella enteritidis strains were determined. Small plasmids were present in 59% of the isolates, together with a serotype-specific (38 MDa) plasmid. A correlation was found between the presence of the small plasmid and phage restriction to two phages used for subdividing the Hungarian phage types 1 (PT1) and 6 (PT6) of S. enteritidis (corresponding to PT1 and PT4 in Ward's typing scheme, respectively).

摘要

1990年至1994年间,共对16505株源自人类、动物和食物的肠炎沙门氏菌菌株进行了噬菌体分型,采用匈牙利分型方案,并监测了主要噬菌体类型发病率的变化。1990年至1992年间,PT1(对应于Ward的PT1)的发病率非常高(占肠炎沙门氏菌分离株总数的67.9%-71.0%),后来有所下降。直到1992年,PT6(对应于Ward的PT4)的流行率都很低,之后逐渐上升。测定了78株肠炎沙门氏菌菌株的噬菌体类型和质粒含量。59%的分离株中存在小质粒,同时还有一种血清型特异性(38 MDa)质粒。发现小质粒的存在与噬菌体对用于细分肠炎沙门氏菌匈牙利噬菌体类型1(PT1)和6(PT6)(分别对应于Ward分型方案中的PT1和PT4)的两种噬菌体的限制性之间存在相关性。

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