Kong W, Egg G, Schrott-Fischer A, Hussl B
Department of Otolaryngology, Xiehe Hospital, Tongji Medical University, Wuhan.
J Tongji Med Univ. 1997;17(1):57-60, 64. doi: 10.1007/BF02888005.
The innervation of cholinergic efferent fibers in the vestibular endorgans of the rats was investigated using a modified preembedding immunostaining technique of immunoelectron microscopy. A monoclonal antibody to choline acetyltransferase (ChAT) was used as a marker of cholinergic fibers. It was found that there were four types of cholinergic innervation in the vestibular endorgans of the rat: (1) cholinergic nerve endings formed axo-dendritic synapses with afferent chalice surrounding the type I sensory hair cells; (2) cholinergic nerve endings formed axo-somatic synapses with type II hair cells; (3) cholinergic fibers synapse with afferent nerve fibers and (4) a synaptic contact developed between cholinergic nerve endings. The results demonstrated that a multiform innervation of the cholinergic efferents exists in the rats vestibular periphery.
采用改良的免疫电镜包埋前免疫染色技术，对大鼠前庭终器中胆碱能传出纤维的神经支配进行了研究。使用抗胆碱乙酰转移酶（ChAT）的单克隆抗体作为胆碱能纤维的标志物。结果发现，大鼠前庭终器中存在四种类型的胆碱能神经支配：（1）胆碱能神经末梢与围绕I型感觉毛细胞的传入杯状结构形成轴-树突触；（2）胆碱能神经末梢与II型毛细胞形成轴-体突触；（3）胆碱能纤维与传入神经纤维形成突触；（4）胆碱能神经末梢之间形成突触联系。结果表明，大鼠前庭外周存在胆碱能传出纤维的多种形式神经支配。
