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1993 - 1996年阿根廷内乌肯省的汉坦病毒肺综合征

Hantavirus pulmonary syndrome in the Province of Rio Negro, Argentina, 1993-1996.

作者信息

Cantoni G, Lazaro M, Resa A, Arellano O, Amestoy A M, De Bunder S, Herrero E, Perez A, Larrieu E

机构信息

San Carlos de Bariloche Hospital, Bariloche, Argentina.

出版信息

Rev Inst Med Trop Sao Paulo. 1997 Jul-Aug;39(4):191-6. doi: 10.1590/s0036-46651997000400002.

DOI:10.1590/s0036-46651997000400002
PMID:9640780
Abstract

Early in 1995 the first case of Hantavirus Pulmonary Syndrome was serologically confirmed in El Bolsón (Province of Río Negro, Argentina), corresponding to the third outbreak reported in Argentina. A total of 26 cases of HPS related to the Andean region of Rio Negro Province, were reported from 1993 to 1996, 17 in El Bolsón, 4 in San Carlos de Bariloche, and 5 in Buenos Aires. The incidence rate was 5.03 x 100,000 with a mortality rate of 51.85 x 100. The occurrence of cases was mainly seasonal, with a significantly greater number in the spring, and the persons affected mainly lived in urban or periurban areas. In four cases, the affected individuals were members of a couple, spouses or live-in contacts. Seven cases were Health workers (physicians, nurses or administrative staff). Twelve cases were related among them, due to an outbreak of 80 days. Two of them did not visit the Andean region. A total of 139 rodents were captured and seven of them, Olygoryzomys longicaudatus, were found to be serologically positive. The possibility of infection by contact with rodents or fecal matter is being analyzed and also hypothesis related with interhuman transmission.

摘要

1995年初,阿根廷内乌肯省埃尔博尔松首次血清学确诊汉坦病毒肺综合征病例,这是阿根廷报告的第三起疫情。1993年至1996年,共报告了26例与内乌肯省安第斯地区相关的汉坦病毒肺综合征病例,其中17例在埃尔博尔松,4例在圣卡洛斯-德巴里洛切,5例在布宜诺斯艾利斯。发病率为5.03/10万,死亡率为51.85/100。病例发生主要呈季节性,春季病例数显著增多,患者主要居住在城市或城郊地区。有4例患者为夫妻、配偶或同居接触者。7例为卫生工作者(医生、护士或行政人员)。12例病例相互关联,因一次持续80天的疫情所致。其中2例未去过安第斯地区。共捕获139只啮齿动物,其中7只长尾稻鼠血清学检测呈阳性。目前正在分析通过接触啮齿动物或粪便感染的可能性,以及与人际传播相关的假设。

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