Ríos-Martín J J, Parra-Martín J A, Gómez-Pascual A, Hevia-Vázquez A, González-Cámpora R
Department of Pathology, University Hospital Virgen Macarena, Seville, Spain.
J Dermatol. 1998 May;25(5):314-21. doi: 10.1111/j.1346-8138.1998.tb02404.x.
We report the histological, immunohistochemical and ultrastructural findings of an exophytic cutaneous tumor composed of a mixture of typical basal cell carcinoma (BCC) and malignant fibrous histiocytoma. Nine previously reported carcinosarcomas of the skin are reviewed. We prefer the term "sarcomatoid carcinoma" for this rare neoplasm. Only the BCC showed a positive immunoreaction to cytokeratin; the sarcomatous component was negative, but it did express vimentin, and, focally, smooth-muscle-specific actin and KP1 (CD68). Both components showed p53 immunostaining.
我们报告了一例由典型基底细胞癌（BCC）和恶性纤维组织细胞瘤混合组成的外生性皮肤肿瘤的组织学、免疫组织化学及超微结构检查结果。对9例先前报道的皮肤癌肉瘤进行了回顾。我们更倾向于用“肉瘤样癌”这一术语来描述这种罕见肿瘤。仅基底细胞癌对细胞角蛋白呈阳性免疫反应；肉瘤成分呈阴性，但表达波形蛋白，且局灶性表达平滑肌特异性肌动蛋白和KP1（CD68）。两种成分均显示p53免疫染色阳性。
