Seeger R, Bartels O
Dtsch Med Wochenschr. 1976 Oct 1;101(40):1456-8.
Charcoal perfusion in vitro resulted in virtually complete detoxication of an extract from 170 g of Amanita phalloides in aqueous or plasma protein solution. After 4 min of perfusion the amanitin content was reduced to 1-2% after 15 min it was less than 1% of the starting material. Under the same conditions toadstool toxin was eliminated from plasma protein solution too: after 4 min of perfusion a dose of remaining material, corresponding to the LD70 of the starting material, was nontoxic in mice.
体外木炭灌注能使170克毒鹅膏菌在水或血浆蛋白溶液中的提取物几乎完全解毒。灌注4分钟后，鹅膏毒肽含量降至1%-2%，15分钟后，其含量不到起始物质的1%。在相同条件下，血浆蛋白溶液中的蛤蟆菌毒素也被清除：灌注4分钟后，相当于起始物质LD70的剩余物质剂量对小鼠无毒。
