Musalatov Kh A, Gordeev P S, Mindadze N A
Khirurgiia (Mosk). 1998(5):18-20.
In order to study iron metabolism disorders in patients with portal hypertension syndrome, to determine clinical significance of hyposiderosis and to work out effective method of its correction, 94 patients with cirrhosis of the liver complicated by portal hypertension were examined. As a result of determination of these disorders of iron metabolism methods for treatment of hypochromal anemia and hyposiderosis have been worked out. Hemotransfusions, administration of iron-containing preparation Ferrum-lec and combination of these methods were used for treatment. It was established that administration of large doses of iron-containing preparation Ferrum-lec substantially contributed to improvement of iron metabolism in patients with cirrhosis of the liver and extrahepatic portal hypertension, to reduction of postoperative complications rate and to upgrading the results of surgical treatment.
为研究门脉高压综合征患者的铁代谢紊乱,确定低铁血症的临床意义并找出有效的纠正方法,对94例肝硬化合并门脉高压患者进行了检查。通过对这些铁代谢紊乱的测定,制定出了治疗低色素性贫血和低铁血症的方法。采用了输血、给予含铁制剂Ferrum-lec以及两者结合的方法进行治疗。结果表明,给予大剂量含铁制剂Ferrum-lec对改善肝硬化和肝外门脉高压患者的铁代谢、降低术后并发症发生率以及提高手术治疗效果有很大帮助。