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淋巴瘤的骨髓受累:骨髓磁共振成像的重要性

Bone marrow involvement in lymphoma: the importance of marrow magnetic resonance imaging.

作者信息

Takagi S, Tsunoda S, Tanaka O

机构信息

Division of Hematology and Department of Radiology, Omiya Medical Center, Jichi Medical School, Omiya Saitama, Japan.

出版信息

Leuk Lymphoma. 1998 May;29(5-6):515-22. doi: 10.3109/10428199809050911.

DOI:10.3109/10428199809050911
PMID:9643565
Abstract

Detection of bone marrow involvement is important for staging and treatment decisions in patients with lymphoma. Although routine bone marrow evaluation is based on aspirates and bone marrow biopsies, new diagnostic tools are required to improve diagnostic accuracy. Visual and quantitative assessment of the bone marrow by magnetic resonance (MR) imaging is useful for the detection of occult lymphomatous marrow involvement. MRI is also suitable for the evaluation of disease extent in the bone marrow. Furthermore, abnormal images on marrow MRI may be associated with a significantly poorer survival in patients with lymphoma, regardless of histologic findings in the marrow. Evaluation of the bone marrow by MRI is essential to assess disease status in patients with lymphoma.

摘要

检测骨髓受累情况对于淋巴瘤患者的分期和治疗决策至关重要。尽管常规骨髓评估基于骨髓穿刺和骨髓活检,但仍需要新的诊断工具来提高诊断准确性。通过磁共振(MR)成像对骨髓进行视觉和定量评估,有助于检测隐匿性淋巴瘤骨髓受累情况。MRI也适用于评估骨髓中疾病的范围。此外,无论骨髓的组织学表现如何,骨髓MRI上的异常图像可能与淋巴瘤患者显著较差的生存率相关。通过MRI评估骨髓对于评估淋巴瘤患者的疾病状态至关重要。

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