Dehydroradiosumin, a trypsin inhibitor from the cyanobacterium Anabaena cylindrica.

作者信息

Kodani S, Ishida K, Murakami M

机构信息

Laboratory of Marine Biochemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Bunkyo-ku, Tokyo 113, Japan.

出版信息

J Nat Prod. 1998 Jun 26;61(6):854-6. doi: 10.1021/np980048e.

DOI:10.1021/np980048e

PMID:9644086

Abstract

Dehydroradiosumin, a novel potent trypsin inhibitory dipeptide, was isolated from the freshwater cyanobacterium Anabaena cylindrica (NIES-19). Its structure was elucidated as 1 on the basis of 2D NMR data and chemical degradation. The IC50 of 1 against trypsin was 0.1 microg/mL.

摘要