用五肽胃泌素或长效组胺对大鼠进行长期预处理后，大鼠对胆碱能刺激的胃分泌反应。
Gastric secretory response to cholinergic stimulation in rats chronically pretreated with pentagastrin or histamine in depot form.
作者信息
Kowalewski K
出版信息
Digestion. 1976;14(4):368-71. doi: 10.1159/000197954.
PMID:964477
Abstract
Rats pretreated by daily depot injections of pentagastric for 24 days, responded with a significant increase of gastric secretion volume, and HC1 concentration and output, when infused intravenously with bethanechol chloride. In these rats, the total weight of the stomach and the height of the fundic mucosa were also increased. Pretreatment with histamine had no effect on rat gastric tissue or gastric secretion, under identical conditions of stimulation.
摘要
通过每日 depot 注射五肽胃泌素预处理 24 天的大鼠，在静脉注射氯贝胆碱时，胃分泌量、盐酸浓度和排出量显著增加。在这些大鼠中，胃的总重量和胃底黏膜高度也增加。在相同刺激条件下，用组胺预处理对大鼠胃组织或胃分泌没有影响。
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