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[临床前血气分析。1. 临床前血气分析的价值]

[Preclinical blood gas analysis. 1. The value of preclinical blood gas analysis].

作者信息

Prause G, Hetz H, Doppler R

机构信息

Universitätsklinik für Anästhesiologie und Intensivmedizin LKH Graz.

出版信息

Anaesthesist. 1998 May;47(5):400-5. doi: 10.1007/s001010050576.

Abstract

UNLABELLED

Prehospital blood gas analysis is a new method in out-of-hospital emergency care. In a prospective pilot study we evaluated the feasibility of prehospital compensation of severe acidosis relying on different monitoring systems to evaluate patients oxygen, carbon dioxide or acid-base status, respectively.

METHODS

With the help of arterial blood gas checks taken at the site of the emergency, the acid base status of patients undergoing out of hospital cardiopulmonary resuscitation was analysed. The values derived from the first arterial puncture were used to determine the presence and the type of acidosis. The data of the arterial blood gas checks were set into relation with the time elapsed since the beginning of resuscitation and they were compared with end-tidal CO2.

RESULTS

During the observation period 26 blood gas analyses from patients who had out-of-hospital resuscitation because of cardiac arrest were done. Twenty three patients had severe acidosis (pH range < 6.9 to 7.31), one had alkalosis (pH 7.51). Only two had an arterial pH within normal range. The pCO2 was variable (range: 24 to 97 mm Hg). The correlation of pH with time from the beginning of resuscitation to arterial puncture was poor (r = 0.407, p < 0.05). There was no correlation between pH and BE (r = 0.267) or pH and pCO2, (r = 0.016) respectively. Prehospital capnometry had a poor correlation with arterial pCO2 in most emergency patients. Only patients with respiratory disturbances of extrapulmonary origin showed a good correlation between end-tidal CO2 and the arterial pCO2. In severely ill patients the arterio-alveolar CO2-difference was unexpectedly high (> 15 mm Hg). In four patients resuscitation was not successful until compensation of an unexpectedly severe acidosis based upon the findings from blood-gas analysis had been performed.

CONCLUSIONS

Arterial blood gas analysis proved to be helpful in the optimal management of out of hospital cardiac arrest. The incidence of severe acidosis in patients undergoing cardiopulmonary resuscitation was 80%. The probability of developing acidosis was found to increase slightly depending on the time elapsed since the beginning of CPR. The application of a calculated buffering of acidosis with sodium bicarbonate showed a good outcome in selected cases. In emergency patients alternative methods fail to detect severe disturbances of the patients oxygen and/or carbon dioxide status and the acid-base balance. Management of prehospital cardiac arrest could be optimized by the routine use of blood gas analysis.

摘要

未标注

院前血气分析是院外急救护理中的一种新方法。在一项前瞻性试点研究中,我们评估了依靠不同监测系统分别评估患者氧、二氧化碳或酸碱状态来对严重酸中毒进行院前纠正的可行性。

方法

借助在急救现场采集的动脉血气检查结果,分析院外心肺复苏患者的酸碱状态。首次动脉穿刺所得数值用于确定酸中毒的存在及类型。将动脉血气检查数据与复苏开始后的时间相关联,并与呼气末二氧化碳进行比较。

结果

在观察期内,对因心脏骤停接受院外复苏的患者进行了26次血气分析。23例患者存在严重酸中毒(pH范围<6.9至7.31),1例存在碱中毒(pH 7.51)。仅2例患者的动脉pH值在正常范围内。pCO2值变化较大(范围:24至97毫米汞柱)。从复苏开始至动脉穿刺时pH与时间的相关性较差(r = 0.407,p < 0.05)。pH与碱剩余(r = 0.267)或pH与pCO2(r = 0.016)之间均无相关性。在大多数急诊患者中,院前二氧化碳监测与动脉pCO2的相关性较差。仅肺外源性呼吸紊乱患者的呼气末二氧化碳与动脉pCO2之间显示出良好的相关性。在重症患者中,动脉 - 肺泡二氧化碳差值意外地高(>15毫米汞柱)。在4例患者中,直到根据血气分析结果对意外严重的酸中毒进行纠正后,复苏才成功。

结论

动脉血气分析被证明有助于对院外心脏骤停进行优化管理。接受心肺复苏患者中严重酸中毒的发生率为80%。发现酸中毒的发生概率随心肺复苏开始后的时间略有增加。在特定病例中,应用计算得出的碳酸氢钠对酸中毒进行缓冲显示出良好的效果。在急诊患者中,其他方法无法检测到患者氧和/或二氧化碳状态以及酸碱平衡的严重紊乱。通过常规使用血气分析可优化院外心脏骤停的管理。

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