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2%莫西菌素口服凝胶剂对肠胃蝇二龄和三龄幼虫的药效

Efficacy of moxidectin 2% oral gel against second- and third-instar Gasterophilus intestinalis De Geer.

作者信息

Scholl P J, Chapman M R, French D D, Klei T R

机构信息

Fort Dodge Animal Health, Princeton, New Jersey 08543-0400, USA.

出版信息

J Parasitol. 1998 Jun;84(3):656-7.

PMID:9645883
Abstract

In a trial designed to evaluate the efficacy of the recommended dosage of moxidectin 2% oral gel against the gastric stages of Gasterophilus spp., 14 ponies were selected from a herd on the basis of the inclusion criterion of the presence of Gasterophilus spp. eggs attached to their hair coats. After random allocation, the ponies were treated with 1 of 2 treatments, moxidectin 2% equine gel in a single dose at the commercial dosage of 400 microg moxidectin/kg body weight or placebo gel. The animals were necropsied 14 days posttreatment. Efficacies against second- and third-instar Gasterophilus intestinalis De Geer were 100% and 99.5%, respectively.

摘要

在一项旨在评估2%莫昔克丁口服凝胶推荐剂量对胃蝇属胃期疗效的试验中,根据毛发上附着有胃蝇属虫卵这一纳入标准,从一群马中挑选出14匹小马。随机分配后,这些小马接受两种处理中的一种,即按400微克莫昔克丁/千克体重的商业剂量单剂量给予2%莫昔克丁马用凝胶或安慰剂凝胶。在处理后14天对动物进行尸检。对肠胃蝇二期和三期幼虫的疗效分别为100%和99.5%。

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