Sievers H H, Gerdes A, Kunze J, Pfister G
Department of Cardiac Surgery, Medical University of Lübeck, Germany.
Ann Thorac Surg. 1998 Jun;65(6):1741-5. doi: 10.1016/s0003-4975(98)00252-5.
In the Fontan circulation, energy consumption at the cavopulmonary connection is crucial. Our hypothesis was that a modification of the standard Norwood variant of cavopulmonary connection with an extended anastomosis would improve hydrodynamics.
The in vitro hydrodynamics of two different Perspex glass models resembling the Norwood variant of cavopulmonary connection (model I) and the modification (model II) were analyzed in a mock circulation at nonpulsatile flows of 2 to 5 L/min to simulate rest and exercise. The pulmonary flow split was varied to imitate varying lung resistances. Inferior-to-superior caval flow ratio and size of models were increased to simulate growth.
The pulmonary flow was preferentially directed to the left lung in model I and was better balanced in model II. Power losses increased exponentially with total flow in both models and were markedly higher in model I. These differences were attenuated in the larger models. Anastomotic turbulences were larger in model I. Power losses in both models were relatively insensitive to changes in pulmonary flow split.
The proposed modification of the Norwood variant of cavopulmonary connection seems to be hydrodynamically advantageous and warrants further evaluation.
在Fontan循环中,腔肺连接部位的能量消耗至关重要。我们的假设是,对标准Norwood式腔肺连接进行改良,采用延长吻合术,将改善流体动力学。
在模拟循环中,对两个不同的有机玻璃模型(分别类似Norwood式腔肺连接(模型I)和改良模型(模型II))进行体外流体动力学分析,非搏动血流速度为2至5升/分钟,以模拟静息和运动状态。改变肺血流分流以模拟不同的肺阻力。增加下腔静脉与上腔静脉血流比以及模型尺寸以模拟生长。
在模型I中,肺血流优先流向左肺,而在模型II中分布更均衡。两个模型中的功率损失均随总血流量呈指数增加,且模型I中的功率损失明显更高。在更大的模型中,这些差异有所减弱。模型I中的吻合口湍流更大。两个模型中的功率损失对肺血流分流变化相对不敏感。
所提议的对Norwood式腔肺连接的改良在流体动力学方面似乎具有优势,值得进一步评估。