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Intestinal absorption of ribavirin is preferentially mediated by the Na+-nucleoside purine (N1) transporter.

作者信息

Patil S D, Ngo L Y, Glue P, Unadkat J D

机构信息

Department of Pharmaceutics, School of Pharmacy, University of Washington, Seattle 98195, USA.

出版信息

Pharm Res. 1998 Jun;15(6):950-2. doi: 10.1023/a:1011945103455.

DOI:10.1023/a:1011945103455
PMID:9647364
Abstract
摘要

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本文引用的文献

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Functional expression of human intestinal Na+-dependent and Na+-independent nucleoside transporters in Xenopus laevis oocytes.人肠道钠依赖性和非钠依赖性核苷转运体在非洲爪蟾卵母细胞中的功能表达。
Biochem Pharmacol. 1997 Jun 15;53(12):1909-18. doi: 10.1016/s0006-2952(97)00170-6.
2
Sodium-dependent nucleoside transport in the human intestinal brush-border membrane.人小肠刷状缘膜中钠依赖性核苷转运
Am J Physiol. 1997 Jun;272(6 Pt 1):G1314-20. doi: 10.1152/ajpgi.1997.272.6.G1314.
3
Nucleoside and nucleobase transport systems of mammalian cells.
用于治疗 COVID-19 的候选药物的药物相互作用：概述。
Pharmacol Res Perspect. 2021 Feb;9(1):e00705. doi: 10.1002/prp2.705.
4
The role of the equilibrative nucleoside transporter 1 on tissue and fetal distribution of ribavirin in the mouse.平衡核苷转运体1在利巴韦林于小鼠体内的组织及胎儿分布中的作用。
Biopharm Drug Dispos. 2016 Sep;37(6):336-44. doi: 10.1002/bdd.2015.
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Biowaiver Monographs for Immediate Release Solid Oral Dosage Forms: Ribavirin.口服速释固体制剂的生物豁免专著：利巴韦林。
J Pharm Sci. 2016 Apr;105(4):1362-9. doi: 10.1016/j.xphs.2016.01.017. Epub 2016 Mar 5.
6
Telaprevir and ribavirin interaction: higher ribavirin levels are not only due to renal dysfunction during triple therapy.替拉普韦与利巴韦林的相互作用：三联疗法期间利巴韦林水平升高不仅是由于肾功能不全。
Antimicrob Agents Chemother. 2015;59(6):3257-62. doi: 10.1128/AAC.04795-14. Epub 2015 Mar 23.
7
Nucleoside transporter proteins as biomarkers of drug responsiveness and drug targets.核苷转运蛋白作为药物反应性和药物靶点的生物标志物。
Front Pharmacol. 2015 Feb 10;6:13. doi: 10.3389/fphar.2015.00013. eCollection 2015.
8
Population pharmacokinetic modeling of plasma and intracellular ribavirin concentrations in patients with chronic hepatitis C virus infection.慢性丙型肝炎病毒感染患者血浆和细胞内利巴韦林浓度的群体药代动力学建模
Antimicrob Agents Chemother. 2015 Apr;59(4):2179-88. doi: 10.1128/AAC.04618-14. Epub 2015 Feb 2.
9
Measurement of intracellular ribavirin mono-, di- and triphosphate using solid phase extraction and LC-MS/MS quantification.使用固相萃取和液相色谱-串联质谱法定量测定细胞内单磷酸、二磷酸和三磷酸利巴韦林。
J Chromatogr B Analyt Technol Biomed Life Sci. 2015 Jan 26;978-979:163-72. doi: 10.1016/j.jchromb.2014.11.032. Epub 2014 Dec 17.
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Physiological parameters in laboratory animals and humans.实验动物和人类的生理参数。
Pharm Res. 1993 Jul;10(7):1093-5. doi: 10.1023/a:1018943613122.
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Nucleoside transport in normal and neoplastic cells.正常细胞与肿瘤细胞中的核苷转运
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Effects of ribavirin on respiratory syncytial virus in vitro.利巴韦林对呼吸道合胞病毒的体外作用。
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8
Inhibitory effects of several antiviral compounds on the replication of respiratory syncytial virus in vitro.
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9
Ribavirin disposition in high-risk patients for acquired immunodeficiency syndrome.利巴韦林在获得性免疫缺陷综合征高危患者中的处置情况。
Clin Pharmacol Ther. 1987 May;41(5):546-55. doi: 10.1038/clpt.1987.70.
10
Sodium-dependent nucleoside transport in mouse intestinal epithelial cells. Two transport systems with differing substrate specificities.小鼠肠道上皮细胞中钠依赖性核苷转运。两种具有不同底物特异性的转运系统。
J Biol Chem. 1988 Dec 25;263(36):19419-23.