Fischer M, Ohlen J, Erhardt W, Secker C, Gartmaier P, Richter J, Stötter L
Fortschr Med. 1976 Apr 22;94(12):689-94.
In order to determine the validity of clinical-chemical parameters for the prognosis of hepatic failure, 28 pigs were subjected to liver ischemia for 40--160 minutes duration. The following parameters were studied: GOT, GPT, gamma-GT, LAP, LDH, GlDH, AP and isoenzymes, total bilirubin, potassium, sodium and chloride. In a statistical comparison in the surviving animals, an unexplainable increase in GlDH activity was observed. In the other clinical-chemical parameters none was seen to be of use for the prognosis for either life or death in acute hepatic failure.
为了确定临床化学参数对肝衰竭预后的有效性，对28头猪进行了持续40 - 160分钟的肝脏缺血实验。研究了以下参数：谷草转氨酶（GOT）、谷丙转氨酶（GPT）、γ-谷氨酰转肽酶（gamma-GT）、亮氨酸氨肽酶（LAP）、乳酸脱氢酶（LDH）、谷氨酸脱氢酶（GlDH）、碱性磷酸酶（AP）及其同工酶、总胆红素、钾、钠和氯。在对存活动物的统计比较中，观察到谷氨酸脱氢酶（GlDH）活性出现了无法解释的升高。在其他临床化学参数中，没有发现任何一个参数对急性肝衰竭的生死预后有帮助。
