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[恶性甲状腺肿。病理解剖与功能标准]

[The malignant struma. Pathological anatomy and functional criteria].

作者信息

Thurner J, Montano G

出版信息

Fortschr Med. 1976 May 20;94(15):879-87.

PMID:964839
Abstract

Description of the pathological anatomy of thyroid cancer with classification into carcinomas, sarcomas and special forms of tumors. Concerning the carcinomas of the thyroid gland, the malignant papilloma (papillary carcinoma) and the medullary amyloid- and calcitonin-producing carcinoma deserve special consideration because of their small malignancy and therefore favourable prognosis. Also the proliferating struma Langhans does not come up to "real" carcinomas (organoid structure of the tumor tissue) concerning the growing speed. All other types of carcinomas, as well as sarcomas, are fast growing malignant tumors, which also place metastases early. The metastasizing struma-adenoma is not a malignant tumor in the sense of the term. In addition, it is necessary to refer to the existing difficulties in marking off clearly structurally sarcomatous tumors of the thyroid gland from carcinomas. Besides, one must emphasize, that thyreostatic substances, also ionizing rays (i.e. radioiodine) can produce considerable tissue-changes with cell polymorphia and that a considerable increase in the number of large-cell eosinophilic adenomas (oncocytomas, Hürthle-cell adenomas) exists. The sclerosizing microcarcinoma (Graham's tumor) is not a carcinoma in the sense of the term.

摘要

甲状腺癌的病理解剖描述,包括癌、肉瘤及特殊类型肿瘤的分类。关于甲状腺癌,恶性乳头状瘤(乳头状癌)和髓样淀粉样蛋白及降钙素产生癌因其恶性程度低、预后良好而值得特别关注。此外,增殖性朗汉斯甲状腺肿在生长速度方面也不符合“真正的”癌(肿瘤组织的类器官结构)。所有其他类型的癌以及肉瘤都是生长迅速的恶性肿瘤,也会早期发生转移。转移性甲状腺腺瘤并非严格意义上的恶性肿瘤。此外,有必要提及在甲状腺结构上区分肉瘤性肿瘤和癌存在的困难。此外,必须强调的是,抗甲状腺物质以及电离射线(如放射性碘)可导致细胞多形性的显著组织变化,并且大细胞嗜酸性腺瘤(嗜酸性细胞瘤、许特莱细胞腺瘤)的数量显著增加。硬化性微癌(格雷厄姆瘤)并非严格意义上的癌。

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