Fukunaga M, Sone T
Department of Nuclear Medicine, Kawasaki Medical School.
Nihon Rinsho. 1998 Jun;56(6):1469-73.
Bone mass measurements are essential in the diagnosis of osteoporosis, the monitoring of its progression, and the evaluation of therapeutical responses. Among various methods of bone mass measurements, single- and dual-X-ray absorptiometry, SXA and DXA, have shown excellent fundamental performance. In this paper, the principles of SXA and DXA; i.e., factors of fundamental performance, such as precision, data-acquisition, and radiation dose, the practice of DXA, recent advances in DXA, such as the lateral spine scan, the measurement of body composition, application to BMD measurement of the bones of small animals and at sites of metal implants, morphometry of the spine, and geometrical measurement in the proxial femur, and clinical applications to osteoporosis were particularly reviewed.
骨量测量对于骨质疏松症的诊断、病情进展监测以及治疗反应评估至关重要。在各种骨量测量方法中,单能和双能X线吸收法(SXA和DXA)展现出了出色的基本性能。本文特别综述了SXA和DXA的原理,即基本性能的因素,如精度、数据采集和辐射剂量;DXA的实践应用;DXA的最新进展,如脊柱侧位扫描、身体成分测量、在小动物骨骼和金属植入部位骨密度测量中的应用、脊柱形态测量以及近端股骨的几何测量;以及在骨质疏松症方面的临床应用。