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从伴放线放线杆菌中分离出的温和噬菌体Aa(phi)23的DNA分析

DNA analysis of temperate bacteriophage Aa(phi)23 isolated from actinobacillus actinomycetemcomitans.

作者信息

Willi K, Meyer J

机构信息

Institute of Preventive Dentistry and Oral Microbiology, Dental Center, University of Basel, Switzerland.

出版信息

Mol Gen Genet. 1998 May;258(4):323-5. doi: 10.1007/s004380050737.

DOI:10.1007/s004380050737
PMID:9648735
Abstract

The DNA of the temperate bacteriophage Aaphi23 isolated from the oral bacterium Actinobacillus actinomycetemcomitans was examined structurally both in the phage head and in the prophage. The DNA in phage particles comprises 44 kb linear molecules with a terminal redundancy of 1.6 kb, which represent circular permutations. Thus, DNA is packaged into phage heads by the headful mechanism. The Aaphi23 prophage is integrated into the host chromosome.

摘要

对从口腔细菌伴放线放线杆菌中分离出的温和噬菌体Aaphi23的DNA在噬菌体头部和原噬菌体中的结构进行了研究。噬菌体颗粒中的DNA由44kb的线性分子组成,末端冗余为1.6kb,代表着环状排列。因此,DNA通过头部充满机制包装到噬菌体头部。Aaphi23原噬菌体整合到宿主染色体中。

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