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Mutations in hepatocyte nuclear factor 1beta are not a common cause of maturity-onset diabetes of the young in the U.K.

作者信息

Beards F, Frayling T, Bulman M, Horikawa Y, Allen L, Appleton M, Bell G I, Ellard S, Hattersley A T

机构信息

Division of Molecular Genetics, Institute of Clinical Science, University of Exeter, Devon, UK.

出版信息

Diabetes. 1998 Jul;47(7):1152-4. doi: 10.2337/diabetes.47.7.1152.

DOI:10.2337/diabetes.47.7.1152
PMID:9648841
Abstract
摘要

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1
Mutations in hepatocyte nuclear factor 1beta are not a common cause of maturity-onset diabetes of the young in the U.K.在英国，肝细胞核因子1β突变并非青少年成年起病型糖尿病的常见病因。
Diabetes. 1998 Jul;47(7):1152-4. doi: 10.2337/diabetes.47.7.1152.
2
Maturity-onset diabetes of the young due to a mutation in the hepatocyte nuclear factor-4 alpha binding site in the promoter of the hepatocyte nuclear factor-1 alpha gene.由于肝细胞核因子-1α基因启动子中肝细胞核因子-4α结合位点发生突变所致的青年发病型成年糖尿病。
Diabetes. 1997 Oct;46(10):1648-51. doi: 10.2337/diacare.46.10.1648.
3
Mutations in the hepatocyte nuclear factor-1alpha gene are a common cause of maturity-onset diabetes of the young in the U.K.在英国，肝细胞核因子-1α基因的突变是青年发病型成年糖尿病的常见病因。
Diabetes. 1997 Apr;46(4):720-5. doi: 10.2337/diab.46.4.720.
4
Linkage and molecular scanning analyses of MODY3/hepatocyte nuclear factor-1 alpha gene in typical familial type 2 diabetes: evidence for novel mutations in exons 8 and 10.典型家族性2型糖尿病中MODY3/肝细胞核因子-1α基因的连锁与分子扫描分析：外显子8和10中新型突变的证据
J Clin Endocrinol Metab. 1998 Jun;83(6):2059-65. doi: 10.1210/jcem.83.6.4874.
5
[Maturity-onset diabetes of the young associated with mutations in HNF-transcription factors].
Nihon Ika Daigaku Zasshi. 1999 Oct;66(5):329-31. doi: 10.1272/jnms.66.329.
6
Hepatocyte nuclear factor 1 alpha (HNF-1 alpha) mutations in maturity-onset diabetes of the young.年轻型成年发病糖尿病中的肝细胞核因子1α（HNF-1α）突变
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Mutations in the genes for hepatocyte nuclear factor (HNF)-1alpha, -4alpha, -1beta, and -3beta; the dimerization cofactor of HNF-1; and insulin promoter factor 1 are not common causes of early-onset type 2 diabetes in Pima Indians.肝细胞细胞核因子（HNF）-1α、-4α、-1β和-3β基因；HNF-1的二聚化辅助因子；以及胰岛素启动因子1的突变并非皮马印第安人早发型2型糖尿病的常见病因。
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8
beta-cell genes and diabetes: molecular and clinical characterization of mutations in transcription factors.β细胞基因与糖尿病：转录因子突变的分子与临床特征
Diabetes. 2001 Feb;50 Suppl 1:S94-100. doi: 10.2337/diabetes.50.2007.s94.
9
An automated fluorescent single-strand conformation polymorphism technique for screening mutations in the hepatocyte nuclear factor-1alpha gene (maturity-onset diabetes of the young).一种用于筛查肝细胞核因子-1α基因（青年发病的成年型糖尿病）突变的自动化荧光单链构象多态性技术。
Diabetes. 1997 Dec;46(12):2108-9. doi: 10.2337/diab.46.12.2108.
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Clinical spectrum associated with hepatocyte nuclear factor-1beta mutations.与肝细胞核因子-1β突变相关的临床谱
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