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受辐照人体中的染色体早熟凝聚。

Premature chromosome condensation in irradiated man.

作者信息

Witkowski R, Anger H

出版信息

Hum Genet. 1976 Sep 10;34(1):65-8. doi: 10.1007/BF00284437.

DOI:10.1007/BF00284437
PMID:965007
Abstract

Micronuclei and premature chromosome condensation previously described in mammalian cells exposed to different types of irradiation and chemicals in vitro or in vivo could be demonstrated in cultured lymphocytes derived from chronically low-dose irradiated persons. The usefulness of these findings for biological recording of irradiation effects is suggested.

摘要

在体外或体内暴露于不同类型辐射和化学物质的哺乳动物细胞中先前已描述过的微核和染色体早熟凝集,在来自长期低剂量受照人员的培养淋巴细胞中也能够被证实。这些发现对于辐射效应的生物学记录的实用性得到了提示。

相似文献

1
Premature chromosome condensation in irradiated man.受辐照人体中的染色体早熟凝聚。
Hum Genet. 1976 Sep 10;34(1):65-8. doi: 10.1007/BF00284437.
2
Premature chromosome condensation in the bone marrow of chinese hamsters after whole body irradiation with Co-60 gamma rays in vivo.
Humangenetik. 1975 Jun 19;28(2):97-102. doi: 10.1007/BF00735741.
3
The human leulocyte test system. VII. Further investigations concerning micronucleus-derived premature chromosome condensation.人类白细胞测试系统。VII. 关于微核衍生的早熟染色体凝聚的进一步研究。
Humangenetik. 1975 Nov 6;30(2):143-54. doi: 10.1007/BF00291947.
4
Analysis of interphase chromosome damage by means of premature chromosome condensation after X- and ultraviolet-irradiation.通过X射线和紫外线照射后早熟染色体凝聚对间期染色体损伤进行分析。
Proc Natl Acad Sci U S A. 1974 Apr;71(4):1137-41. doi: 10.1073/pnas.71.4.1137.
5
Stress induced by premature chromatin condensation triggers chromosome shattering and chromothripsis at DNA sites still replicating in micronuclei or multinucleate cells when primary nuclei enter mitosis.当原核进入有丝分裂时,过早染色质凝聚诱导的应激会在微核或多核细胞中仍在复制的DNA位点引发染色体破碎和染色体碎裂。
Mutat Res Genet Toxicol Environ Mutagen. 2015 Nov;793:185-98. doi: 10.1016/j.mrgentox.2015.07.014. Epub 2015 Jul 29.
6
Premature chromosome condensation. I. Visualization of x-ray-induced chromosome damage in interphase cells.早熟染色体凝集。I. 间期细胞中X射线诱导的染色体损伤的可视化
Mutat Res. 1974 May;23(2):251-8. doi: 10.1016/0027-5107(74)90145-6.
7
[Effect of ultraviolet light on human chromosomes (author's transl)].紫外线对人类染色体的影响(作者译)
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Chromosome aberration in human lymphocytes after X-irradiation in vitro. II. Analysis of primary processes in the formation of dicentric chromosomes.体外X射线照射后人淋巴细胞中的染色体畸变。II. 双着丝粒染色体形成过程中初级过程的分析。
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The relative radiosensitivities of human, rabbit and rat-kangaroo chromosomes.人类、兔和大鼠 - 袋鼠染色体的相对放射敏感性
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Study of the nature of damages to chromosomes of the nuclei of amphibian leukocytes after their irradiation in various phases of the mitotic cycle. I. Irradiation in the G2 phase.两栖类白细胞细胞核在有丝分裂周期各阶段受照射后染色体损伤性质的研究。I. G2期照射。
Sov Genet. 1974 May 1;8(3):321-7.

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2
Cell proliferation and chromosomal damage in human leukocytes: dicentrics and premature chromosome condensations in first, second, and third mitoses after X-irradiation.人类白细胞中的细胞增殖与染色体损伤:X射线照射后第一次、第二次和第三次有丝分裂中的双着丝粒染色体和染色体过早凝聚
Hum Genet. 1981;57(1):75-7. doi: 10.1007/BF00271172.

本文引用的文献

1
["Chromosome pulverization" induced in vitro in cell cultures by sodium diarsenate].[二砷酸钠在细胞培养中体外诱导的“染色体粉碎”]
Arch Klin Exp Dermatol. 1968 May 9;231(4):366-70.
2
The phenomenon of premature chromosome condensation: its relevance to basic and applied research.染色体提前凝聚现象:其与基础研究和应用研究的相关性。
Humangenetik. 1974;23(4):235-58. doi: 10.1007/BF00272508.
3
The human leulocyte test system. VII. Further investigations concerning micronucleus-derived premature chromosome condensation.人类白细胞测试系统。VII. 关于微核衍生的早熟染色体凝聚的进一步研究。
Humangenetik. 1975 Nov 6;30(2):143-54. doi: 10.1007/BF00291947.
4
Premature chromosome condensation in the bone marrow of chinese hamsters after whole body irradiation with Co-60 gamma rays in vivo.
Humangenetik. 1975 Jun 19;28(2):97-102. doi: 10.1007/BF00735741.
5
Premature chromosme condensation in the bone marrow of Chinese hamster after application of bleomycin in vivo.
Mutat Res. 1975 Feb;27(2):285-94. doi: 10.1016/0027-5107(75)90089-5.
6
The human leukocyte test system. III. Premature chromosome condensation from chemically and x-ray induced micronuclei.
Mutat Res. 1975 Jan;27(1):89-101.