Stĕpán J, Záhora R, Poláková L, Krenková J, Masatová A
Laborator pro endokrinologii a metabolismus III. interní klinika I. LF UK a VFN, Praha.
Cas Lek Cesk. 1998 Apr 20;137(8):237-9.
The objective of this study was to evaluate the prevalence of osteoporosis and osteopenia in Czech women and men aged 50 to 75 years.
Bone mineral density was assessed in an age-stratified random sample of 713 women and 429 men from two cities (Prague and Litomĕrice) in the lumbar spine, proximal femur and total body by dual X-ray absorptiometry and in the distal forearm by single X-ray absorptiometry. The proportion of women and men in each age group with bone density below specified levels at any of these skeletal sites was projected to the population structure of the Czech Republic. With advancing age, in women at 55 years and in men at 65 years of age the population with normal bone mineral density becomes smaller, and a greater proportion has osteopenia or osteoporosis. Overall, an estimated 428,000 women and 195,000 men over age 50 have osteoporosis and another 680,000 women and 435,000 men have osteopenia.
The results of this first population-based cross sectional study in the Czech Republic document a high prevalence of osteoporosis and osteopenia which is comparable with that published for the Netherlands and the United States. The results offer a basis for economical considerations in diagnosis, treatment and consequences of osteoporosis.
本研究的目的是评估捷克50至75岁女性和男性骨质疏松症和骨质减少症的患病率。
通过双能X线吸收法对来自布拉格和利托梅尔日采两个城市的713名女性和429名男性按年龄分层的随机样本进行腰椎、股骨近端和全身骨密度评估，通过单能X线吸收法对前臂远端进行骨密度评估。将每个年龄组中在这些骨骼部位任何一处骨密度低于特定水平的女性和男性比例推算至捷克共和国的人口结构。随着年龄增长，55岁女性和65岁男性中骨矿物质密度正常的人群数量减少，骨质减少或骨质疏松的比例增加。总体而言，估计50岁以上的女性中有42.8万人患有骨质疏松症，19.5万人患有骨质减少症；男性中有68万人患有骨质疏松症，43.5万人患有骨质减少症。
捷克共和国这项基于人群的首次横断面研究结果表明，骨质疏松症和骨质减少症的患病率很高，与荷兰和美国公布的数据相当。这些结果为骨质疏松症的诊断、治疗及后果的经济考量提供了依据。
