Kult J
Infusionsther Klin Ernahr. 1976 Apr;3(2):72-7.
The practice of dietetic therapy is unusual today for patients suffering from renal failure without hypertension and reduction of glomerular filtration rate. Specific treatment is needed, however, for arterial hypertension, uremia, calculus and uralith disease. Experiments in rats showed, that a lot of uremic symptoms following poorly functioning kidneys are partly at least caused by disturbances in amino acid metabolism. Uremia patients with dysfunctioning plasma protein metabolism (transferrin, complement, cholinesterase, prealbumin and retinolbinding protein) need oral, respectively parenteral substitution of essential amino acids. This substitution is very important under catabolic stress conditions in uremic syndrome with and without vividialysis treatment.
对于没有高血压且肾小球滤过率降低的肾衰竭患者，如今采用饮食疗法并不常见。然而，对于动脉高血压、尿毒症、结石和尿路结石疾病，则需要进行特定治疗。在大鼠身上进行的实验表明，肾脏功能不佳后出现的许多尿毒症症状至少部分是由氨基酸代谢紊乱引起的。血浆蛋白代谢（转铁蛋白、补体、胆碱酯酶、前白蛋白和视黄醇结合蛋白）功能失调的尿毒症患者需要口服或胃肠外补充必需氨基酸。在有或没有血液透析治疗的尿毒症综合征分解代谢应激状态下，这种补充非常重要。
