Shuren J, Hartley T, Heilman K M
Department of Veterans Affairs Medical Center and the Department of Neurology, University of Florida College of Medicine, Gainesville 32610-0236, USA.
Neuropsychiatry Neuropsychol Behav Neurol. 1998 Apr;11(2):72-5.
Unilateral spatial neglect can be reduced by cold water caloric stimulation of the contralesional ear. Three hypotheses may account for this response. Caloric stimulation may increase the arousal of the damaged hypoaroused hemisphere. Moving stimuli to ipsilesional space improves the performance of patients with neglect. Caloric stimulation may move viewer-centered spatial maps in an ipsilesional direction. Unilateral neglect may be related to a spatial attentional bias. Vestibular stimulation may temporarily influence this bias. To learn if vestibular stimulation may induce an attentional spatial bias, the authors studied eight normal subjects by having these subjects attempt to bisect lines before and during vestibular stimulation. If caloric stimulation alters neglect because it changes the attentional spatial bias, the authors should be able to induce neglect in normal subjects by pertubating the vestibular system. Vestibular stimulation was induced by spinning a chair and then abruptly stopping the spinning chair. The authors found that after normal subjects were rotated to the left, they misbisected lines to the left but did not misbisect lines after they were rotated to the right. Although these results support the postulate that vestibular stimulation can induce an attentional spatial bias, the authors' results also suggest that there are intrinsic attentional asymmetries.
对侧耳的冷水热量刺激可减轻单侧空间忽视。对此反应有三种假说。热量刺激可能会增加受损的低唤醒半球的唤醒程度。将刺激移至同侧空间可改善忽视患者的表现。热量刺激可能会使以观察者为中心的空间地图向同侧方向移动。单侧忽视可能与空间注意力偏差有关。前庭刺激可能会暂时影响这种偏差。为了了解前庭刺激是否会诱发注意力空间偏差，作者通过让八名正常受试者在前庭刺激之前和期间尝试平分线段来对他们进行研究。如果热量刺激改变了忽视情况是因为它改变了注意力空间偏差，那么作者应该能够通过扰动前庭系统在正常受试者中诱发忽视。通过旋转椅子然后突然停止旋转来诱发前庭刺激。作者发现正常受试者向左旋转后，他们会将线段向左平分错误，但向右旋转后不会将线段平分错误。虽然这些结果支持前庭刺激可诱发注意力空间偏差这一假设，但作者的结果也表明存在内在的注意力不对称。
