Goldin J G, Yoon H C, Greaser L E, Nishimura E K
Department of Radiological Sciences, UCLA School of Medicine 90095, USA.
Acad Radiol. 1998 Jul;5(7):503-8. doi: 10.1016/s1076-6332(98)80192-x.
The authors evaluated the sensitivity of electron-beam computed tomography (CT) in the detection of segmental and subsegmental pulmonary artery emboli in a porcine model.
Twenty-one segmental and subsegmental branch pulmonary arteries in five swine were selectively catheterized and embolized with gelatin sponge pledgets. The presence of emboli was confirmed by means of contrast material-enhanced angiography. Contrast-enhanced CT scans of the pulmonary arteries were then obtained with 3-mm collimation, 2-mm table travel between sections, and an imaging time of 100 msec per section. Contrast material was injected at a rate of 2-3 mL/sec, depending on the animal's weight, with a total dose of 60 mL for each scan. Cardiac-gated and nongated scans were obtained, but breath holding was not possible in these animals.
Contrast-enhanced electron-beam CT scanning allowed correct prospective identification of 18 of 21 emboli in the segmental and subsegmental branches of the pulmonary arteries. The overall sensitivity was 86%. Cardiac gating subjectively improved image quality but did not result in greater sensitivity in the detection of emboli. The level of sensitivity was not affected by the use of breath holding.
Contrast-enhanced electron-beam CT is a sensitive method for the detection of embolism in the segmental and subsegmental pulmonary arteries.
作者在猪模型中评估了电子束计算机断层扫描（CT）检测节段性和亚节段性肺动脉栓塞的敏感性。
对5头猪的21个节段性和亚节段性肺动脉分支进行选择性插管，并用明胶海绵小块进行栓塞。通过造影剂增强血管造影确认栓塞的存在。然后以3毫米准直、层间2毫米床移动和每层100毫秒的成像时间进行肺动脉的对比增强CT扫描。根据动物体重，以2 - 3毫升/秒的速率注射造影剂，每次扫描的总剂量为60毫升。进行了心脏门控和非门控扫描，但这些动物无法屏气。
对比增强电子束CT扫描能够前瞻性地正确识别肺动脉节段性和亚节段性分支中21个栓塞中的18个。总体敏感性为86%。心脏门控主观上改善了图像质量，但在检测栓塞方面并未提高敏感性。敏感性水平不受屏气使用的影响。
对比增强电子束CT是检测节段性和亚节段性肺动脉栓塞的一种敏感方法。
