Nakashima T T, McClung R E, Kotovych G
Department of Chemistry, University of Alberta, Edmonton, Alberta, T6G 2G2, Canada.
J Magn Reson. 1998 Jul;133(1):222-6. doi: 10.1006/jmre.1998.1411.
The water "stripes" of the TOCSY maps of aqueous solutions of sucrose, of a 15-aminoacid peptide, and of several of the constituent aminoacids are shown to contain correlations at the resonance frequencies of protons which are scalar coupled to OH or NH protons which exchange with the solvent. Theoretical analysis of chemical exchange during the spin-lock period in TOCSY elucidates the origin of these correlations, and shows that their intensities vary with the duration of the spin-lock period and with the exchange rate.
蔗糖水溶液、一种15氨基酸肽以及几种组成氨基酸的TOCSY图谱中的水“条纹”显示，在与可与溶剂交换的OH或NH质子标量耦合的质子的共振频率处存在相关性。对TOCSY自旋锁定期间化学交换的理论分析阐明了这些相关性的起源，并表明它们的强度随自旋锁定时间和交换速率而变化。
