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Simultaneous detection of cisatracurium, its degradation products and propofol using positive ion detection followed by negative ion detection in a single LC/MS run.

作者信息

Wang P, Zhang H, Stewart J T, Bartlett M G

机构信息

Department of Medicinal Chemistry, College of Pharmacy, University of Georgia, Athens 30602-2352, USA.

出版信息

J Pharm Biomed Anal. 1998 Jul;17(3):547-53. doi: 10.1016/s0731-7085(97)00222-7.

DOI:10.1016/s0731-7085(97)00222-7
PMID:9656168
Abstract
摘要

相似文献

1
Simultaneous detection of cisatracurium, its degradation products and propofol using positive ion detection followed by negative ion detection in a single LC/MS run.在单次液相色谱-质谱联用(LC/MS)运行中,先采用正离子检测,随后采用负离子检测,同时检测顺式阿曲库铵及其降解产物和丙泊酚。
J Pharm Biomed Anal. 1998 Jul;17(3):547-53. doi: 10.1016/s0731-7085(97)00222-7.
2
HPLC determination of cisatracurium besylate and propofol mixtures with LC-MS identification of degradation products.高效液相色谱法测定苯磺顺阿曲库铵与丙泊酚混合物并通过液相色谱-质谱联用鉴定降解产物
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3
Pharmacokinetics and pharmacodynamics of cisatracurium after a short infusion in patients under propofol anesthesia.丙泊酚麻醉下患者短时间输注顺式阿曲库铵后的药代动力学和药效学
Anesth Analg. 1998 Nov;87(5):1158-63. doi: 10.1097/00000539-199811000-00034.
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Determination of atracurium, cisatracurium and mivacurium with their impurities in pharmaceutical preparations by liquid chromatography with charged aerosol detection.采用离子气溶胶检测的高效液相色谱法测定药物制剂中阿曲库铵、顺阿曲库铵和米库氯铵及其杂质。
J Chromatogr A. 2010 Feb 19;1217(8):1266-72. doi: 10.1016/j.chroma.2009.12.025. Epub 2009 Dec 16.
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Recovery from neuromuscular blockade after either bolus and prolonged infusions of cisatracurium or rocuronium using either isoflurane or propofol-based anesthetics.在使用异氟烷或丙泊酚类麻醉剂进行单次推注和长时间输注顺式阿曲库铵或罗库溴铵后,从神经肌肉阻滞中恢复。
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[Effect of sevoflurane versus propofol-remifentanil anesthesia on neuromuscular blockade by continuous cisatracurium infusion].七氟醚与丙泊酚-瑞芬太尼麻醉对持续输注顺式阿曲库铵所致神经肌肉阻滞的影响
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Comparative study of neuromuscular blocking and hemodynamic effects of rocuronium and cisatracurium under sevoflurane or total intravenous anesthesia.七氟醚或全静脉麻醉下罗库溴铵和顺式阿曲库铵对神经肌肉阻滞及血流动力学影响的比较研究
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Cisatracurium-induced neuromuscular block during total intravenous anaesthesia in a patient with Charcot-Marie-Tooth disease.一名患有夏科-马里-图思病的患者在全静脉麻醉期间顺式阿曲库铵诱导的神经肌肉阻滞。
Eur J Anaesthesiol. 2010 Jul;27(7):670-2. doi: 10.1097/EJA.0b013e3283357060.
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Cisatracurium pretreatment with tourniquet reduces propofol injection pain: a double-blind randomized controlled trial.使用止血带时顺式阿曲库铵预处理可减轻丙泊酚注射痛:一项双盲随机对照试验。
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[The effect of different priming doses on the pharmacodynamics of cisatracurium].[不同预注剂量对顺式阿曲库铵药效学的影响]
Anaesthesist. 2000 Feb;49(2):102-5. doi: 10.1007/s001010050015.

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1
An analytical strategy for quaternary ammonium neuromuscular blocking agents in a forensic setting using LC-MS/MS on a tandem quadrupole/time-of-flight instrument.在法医环境中,使用串联四极杆/飞行时间仪器上的液相色谱-串联质谱法分析季铵类神经肌肉阻滞剂的分析策略。
J Am Soc Mass Spectrom. 2006 Oct;17(10):1457-1468. doi: 10.1016/j.jasms.2006.06.026. Epub 2006 Aug 2.
2
Mass spectral fragmentation of the intravenous anesthetic propofol and structurally related phenols.
J Am Soc Mass Spectrom. 2005 Jun;16(6):814-24. doi: 10.1016/j.jasms.2005.02.009. Epub 2005 Mar 24.