Saitou M, Niitsuma K, Kasukawa R
Department of Internal Medicine, Aizu General Hospital, Aizu-Wakamatsu, Japan.
Nihon Kokyuki Gakkai Zasshi. 1998 Mar;36(3):251-5.
Varicella pneumonia is the most common complication of adult varicella. Symptoms may be severe and the mortality rate high in patients who are immunodeficient or pregnant. Symptoms may be mild and progression more favorable in adults previously in good health. We report two cases of varicella infection complicated by severe pulmonary involvement in adult patients who were previously healthy. Case 1 was a 36-year-old male who 6 days after developing varicella was clinically observed to have dyspnea and hemopytsis. He died of acute respiratory failure on the following day. Case 2 was a 28-year-old male whose respiratory symptoms started the third day after developing varicella. These symptoms were relieved by treatment with acyclovir and gammaglobulin. Careful observation is and an early treatment of varicella should be undertaken not only for patients with suppressed cellular immunity, but also for healthy adults, to prevent severe complications.
水痘肺炎是成人水痘最常见的并发症。对于免疫功能低下或怀孕的患者,症状可能严重,死亡率高。对于既往健康的成年人,症状可能较轻,病情进展更有利。我们报告两例既往健康的成年患者发生水痘感染并伴有严重肺部受累的病例。病例1是一名36岁男性,患水痘6天后临床观察到有呼吸困难和咯血。次日死于急性呼吸衰竭。病例2是一名28岁男性,其呼吸道症状在患水痘第三天开始出现。这些症状通过阿昔洛韦和丙种球蛋白治疗得到缓解。不仅对于细胞免疫受抑制的患者,而且对于健康成年人,都应仔细观察并尽早治疗水痘,以预防严重并发症。