Dennis M, Furness L, Lindesay J, Wright N
Division of Psychiatry for the Elderly, Leicester General Hospital, UK.
Int J Geriatr Psychiatry. 1998 Jun;13(6):405-9. doi: 10.1002/(sici)1099-1166(199806)13:6<405::aid-gps785>3.0.co;2-k.
With the development of pharmacological treatments for Alzheimer's disease there will be an increase in the numbers of patients requiring assessment from specialist services. Could the role of the specialist clinician be supported by other health professionals screening those who might benefit from treatment?
Sixty-four consecutive referrals to the Leicester University Memory Clinic were assessed at home by a community psychiatric nurse using a semi-structured interview. The nurse then reported her findings to a psychiatrist and a diagnosis was agreed. This diagnosis was then compared to the Memory Clinic diagnosis and a standardized (ICD-10) diagnosis recorded by another psychiatrist examining the clinic records.
The nurse assessment procedure performed well in detecting dementia, with a kappa statistic (k) of 0.75 when compared to the standardized and Memory Clinic diagnoses. There was, however, only moderate concordance between the ICD-10 diagnosis and nurse (k = 0.46) and the Memory Clinic and nurse (k = 0.60) for Alzheimer's disease. The relatively low k value for Alzheimer's disease was principally a result of difficult in differentiating vascular dementia.
A single supervised community psychiatric nurse, using a structured assessment instrument, can adequately detect early dementia in a sample of patients referred with memory problems. Subtypes of dementia are not, however, accurately differentiated.
随着阿尔茨海默病药物治疗的发展,需要专科服务进行评估的患者数量将会增加。其他健康专业人员对那些可能从治疗中获益的患者进行筛查,能否辅助专科临床医生的工作?
社区精神科护士采用半结构式访谈在家中对连续转诊至莱斯特大学记忆诊所的64名患者进行评估。然后,护士将她的评估结果报告给一名精神科医生,并达成诊断共识。接着,将该诊断结果与记忆诊所的诊断以及另一名查阅诊所记录的精神科医生做出的标准化(ICD - 10)诊断进行比较。
与标准化诊断和记忆诊所诊断相比,护士评估程序在检测痴呆方面表现良好,kappa统计量(k)为0.75。然而,在阿尔茨海默病的诊断上,ICD - 10诊断与护士诊断之间(k = 0.46)以及记忆诊所诊断与护士诊断之间(k = 0.60)仅有中等程度的一致性。阿尔茨海默病相对较低的k值主要是由于难以区分血管性痴呆。
一名经过监督的社区精神科护士,使用结构化评估工具,能够在因记忆问题转诊的患者样本中充分检测出早期痴呆。然而,痴呆的亚型无法得到准确区分。