Demoly P, Jaffuel D, Sahla H, Bousquet J, Michel F B, Godard P
Hôpital Arnaud de Villeneuve, Montpellier, France.
Respir Med. 1998 Apr;92(4):624-7. doi: 10.1016/s0954-6111(98)90507-8.
Nebulization therapy is an approach for the treatment of respiratory diseases such as asthma which was not anticipated in the international recommendations for the treatment of asthma and which merits study. Even if the place of nebulizers in the treatment of asthma exacerbations has been validated, this is not the case for adult asthmatic subjects with chronic asthma. While asthma control for most patients can be achieved using metered-dose inhaler and dry powder inhaler therapy, some patients may require regular home nebulized therapy. Before determining the objectives and therapeutic characteristics of nebulization in the treatment of chronic asthma in the adult patient, we shall first describe the pathophysiological elements involved in the treatment of asthma and of the couple 'nebulized substance-nebulizer' leading to an optimal nebulization.
雾化治疗是一种治疗哮喘等呼吸系统疾病的方法,国际哮喘治疗指南中并未预期到这种方法,值得进行研究。即使雾化器在哮喘急性加重治疗中的地位已得到验证,但对于患有慢性哮喘的成年哮喘患者而言并非如此。虽然大多数患者使用定量吸入器和干粉吸入器治疗可以实现哮喘控制,但一些患者可能需要定期在家进行雾化治疗。在确定雾化治疗成年慢性哮喘患者的目标和治疗特性之前,我们首先将描述哮喘治疗中涉及的病理生理因素,以及导致最佳雾化效果的“雾化药物-雾化器”组合。