[恶性贫血中的胃类癌肿瘤]

Meyer D, Brynskov J, Federspiel B H, Hippe E

Medicinsk-haematologisk afdeling L, Amtssygehuset i Herlev.

Ugeskr Laeger. 1998 Jun 29;160(27):4077-9.

A case of a 39 year-old woman with recently diagnosed PA and a GCT is reported. Recent surveys have shown that GCTs occur far more frequently in patients with chronic atrophic gastritis type A (+/- PA) than previously noted. This may be due to an improved endoscopic technique and the use of specific immunostains, such as chromogranin A, which in our case was essential in avoiding the diagnostic pitfall of an adenocarcinoma. The pathogenesis and the management of type-1 GCT are discussed.

报告了一例39岁近期诊断为自身免疫性胃炎（PA）和胃神经内分泌肿瘤（GCT）的女性病例。近期调查显示，GCT在慢性A型萎缩性胃炎（±PA）患者中的发生率比之前报道的要高得多。这可能是由于内镜技术的改进以及使用了特定的免疫染色，如嗜铬粒蛋白A，在我们的病例中，这对于避免腺癌的诊断陷阱至关重要。本文讨论了1型GCT的发病机制和治疗方法。