Patton L L, McKaig R
Department of Dental Ecology, School of Dentistry, University of North Carolina, Chapel Hill 27599-7450, USA.
J Periodontol. 1998 Jun;69(6):710-6. doi: 10.1902/jop.1998.69.6.710.
This report describes a case of rapidly progressive periodontal tissue breakdown and bone loss in an HIV-infected markedly immunosuppressed homosexual male. Within 6 months of initial presentation with a necrotizing ulcerative gingivitis, the lesion extended to a necrotizing ulcerative stomatitis involving the surrounding periodontium and palatal mucosa. With only partial compliance to local debridement, chlorhexidine oral rinses, and systemic metronidazole therapy, alveolar bone loss resulted in tooth mobility necessitating extraction of 2 involved teeth. This case illustrates the continuum of necrotizing ulcerative infections of the periodontium in the severely immunosuppressed patient. The implications of these oral manifestations of HIV infection are discussed.
本报告描述了一例在感染HIV且免疫功能明显受抑制的同性恋男性中，牙周组织迅速进展性破坏和骨质流失的病例。在最初表现为坏死性溃疡性牙龈炎后的6个月内，病变扩展至坏死性溃疡性口炎，累及周围牙周组织和腭黏膜。仅部分依从局部清创、洗必泰口腔冲洗和全身甲硝唑治疗，牙槽骨丧失导致牙齿松动，致使2颗受累牙齿不得不拔除。该病例说明了严重免疫抑制患者牙周坏死性溃疡性感染的连续性。文中讨论了这些HIV感染口腔表现的意义。
