[在慢性感染细胞培养物中长时间持续存在的蜱传脑炎病毒的特性]
[Properties of the tick-borne encephalitis virus persisting for a long time in a chronically infected cell culture].
作者信息
Andzhaparidze O G, Bogomolova N N, Boriskin Iu S
出版信息
Vopr Virusol. 1978 Mar-Apr(2):192-5.
The biological properties of tick-borne encephalitis virus (Sof K) produced by chronically infected HEp-2-Sof cells at late stages of the cultivation were studied. The Sof K virus was infective for mice of different ages upon intracerebral and subcutaneous inoculation, had high immunogenicity and was completely neutralized by antiserum to the parental strain. The Sof K virus had the small-plaque phenotype and replicated with similar intensity in pig embryo cell cultures (SPEC) at 36 degrees, 42 degrees and 31 degrees C.
研究了在培养后期由慢性感染的HEp-2-Sof细胞产生的蜱传脑炎病毒（Sof K）的生物学特性。Sof K病毒经脑内和皮下接种后对不同年龄的小鼠具有感染性，具有高免疫原性，并被亲本株抗血清完全中和。Sof K病毒具有小斑块表型，在36℃、42℃和31℃的猪胚胎细胞培养物（SPEC）中以相似强度复制。
Zotero 插件