Zykova V P, Afonina I P, Zadoia A A
Kardiologiia. 1976 Feb;16(2):68-73.
From the blood plasma of 34 patients with ischemic heart disease and hyperlipoproteinemia and without it and in 10 practically healthy persons prostaglandins E, A and F2alpha were isolated and the proportion of each one of them was determined by the radioimmunological method. Changes in the quantitative composition of the blood plasma prostaglandins in patients with ischemic heart disease and hyperlipoproteinemia were disclosed, these changes suggesting the participation of the substances in question in the pathogenesis of atherosclerosis.
从34例患有缺血性心脏病和高脂蛋白血症以及未患该病的患者的血浆中,以及10名实际健康人的血浆中分离出前列腺素E、A和F2α,并通过放射免疫法测定它们各自的比例。揭示了缺血性心脏病和高脂蛋白血症患者血浆前列腺素定量组成的变化,这些变化表明上述物质参与了动脉粥样硬化的发病机制。