Suppr超能文献

电耳蜗图在梅尼埃病诊断中的应用。

Use of electrocochleography in the diagnosis of Meniere's disease.

作者信息

Levine S, Margolis R H, Daly K A

机构信息

University of Minnesota Hospital and Clinic, Minneapolis 55455, USA.

出版信息

Laryngoscope. 1998 Jul;108(7):993-1000. doi: 10.1097/00005537-199807000-00008.

Abstract

OBJECTIVE

The diagnosis of Meniere's disease has always been a source of confusion. There is no single test that is definitive for the diagnosis. Recent advances have enabled clinicians to noninvasively test the function of the inner ear and its associated neural pathways. The electrocochleogram (ECOG) has been advocated as a reliable test that is diagnostic for Meniere's disease. This study was undertaken to assess the value of ECOG in establishing the diagnosis of Meniere's disease.

STUDY DESIGN

Patients who were suspected of having Meniere's disease were prospectively entered into a study of the diagnostic value of ECOG. Each patient had a complete evaluation including a detailed history, physical examination, laboratory studies, and audiometric tests.

SETTING

University otolaryngology clinic.

PATIENTS

A group of 199 patients who presented to a neurotology clinic and were suspected to have symptoms consistent with Meniere's disease.

INTERVENTION

ECOG testing.

MAIN OUTCOME MEASURES

Audiometric thresholds, action potential magnitude (AP), summating potential amplitude (SP), AP latency, and clinical evaluations were assessed.

RESULTS

The ECOG was found to correlate with historical and audiometric criteria that are used to diagnose the disease. The percentage of abnormal ECOG did not correlate with stage of disease or duration of time that symptoms were present.

CONCLUSIONS

The ECOG has limited value in the diagnosis of Meniere's disease. It appears to correlate with the length of time patients experience symptoms and their audiometric findings. It was not correlated with the number of symptoms that the patient experienced at the time that the study was conducted.

摘要

目的

梅尼埃病的诊断一直是个令人困惑的问题。没有单一的检查能确诊该病。近年来的进展使临床医生能够非侵入性地检测内耳及其相关神经通路的功能。耳蜗电图(ECOG)被认为是诊断梅尼埃病的可靠检查。本研究旨在评估ECOG在梅尼埃病诊断中的价值。

研究设计

前瞻性纳入疑似梅尼埃病的患者,进行ECOG诊断价值的研究。每位患者均接受了全面评估,包括详细的病史、体格检查、实验室检查和听力测试。

研究地点

大学耳鼻喉科诊所。

患者

一组199例到神经耳科诊所就诊、疑似有符合梅尼埃病症状的患者。

干预措施

ECOG检测。

主要观察指标

评估听力阈值、动作电位幅度(AP)、总和电位幅度(SP)、AP潜伏期及临床评估情况。

结果

发现ECOG与用于诊断该病的病史及听力标准相关。ECOG异常的百分比与疾病分期或症状出现的时间长短无关。

结论

ECOG在梅尼埃病的诊断中价值有限。它似乎与患者出现症状的时间长短及其听力检查结果相关。它与研究进行时患者经历的症状数量无关。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验