Lisch K
Klin Monbl Augenheilkd. 1976 Mar;168(3):330-7.
Three sisters, one brother, and the father of a female patient with primary hydrophthalmus on both eyes had abnormally great physiologic cups. The cup/disc ratio was between 0.5 and 0.72. Two other brothers showed a cup/disc ratio between 0.37 and 0.42, whereas the mother had a cup/disc ratio of 0.2 on both sides. The enlarged physiologic cups of the sisters, the brother, and the father of the propositus correspond to the 4th category of the classification according to Elschnig. Like the hydrophthalmus as a result of a functional disturbance of the eye cup, the occurrence of abnormally big physiologic cups is also referred to the organizing and forming effects of the eye cup. Whether there exists an intrafamiliar relationship between the hydrophthalmus and the abnormally big physiologic cups or not is to be elucidated by further investigations.
三姐妹、一个兄弟以及一名双眼原发性水眼症女性患者的父亲均有异常大的生理杯盘。杯盘比在0.5至0.72之间。另外两个兄弟的杯盘比在0.37至0.42之间，而母亲双侧杯盘比为0.2。先证者的姐妹、兄弟和父亲的生理性杯盘增大符合埃尔施尼格分类的第4类。如同因眼杯功能障碍导致的水眼症一样，异常大的生理性杯盘的出现也归因于眼杯的组织和形成作用。水眼症与异常大的生理性杯盘之间是否存在家族内关系有待进一步研究阐明。
