Demeler U, von Domarus D
Klin Monbl Augenheilkd. 1976 Mar;168(3):387-95.
Report on a rare case of an iris-ringmelanoma. Arising from the iris base the primary tumor spread in a continuous line along the anterior chamber angle and a shedding of tumor cells in other places of the iris surface could be stated as well. A unilateral dark spotted colouring of the iris with a secondary glaucoma was clinically observed. Gonioscopy, diaphanoscopy, 32P-test, and iris fluorescence-angiography aided the diagnosis. Fluorescence angiography appears to be of particular value in the diagnosis of malignant melanoma of the iris: The peculiar filling pattern seen at the pupillary border of the tumor has up to now only been found in malignant processes of the anterior uvea. The clinical tentative diagnosis of malignant ringmelanoma of the iris, could histopathologically be verified.