Galli-Resta L
Istituto di Neurofisiologia CNR, via San Zeno 51, Pisa, 56127, Italy.
Semin Cell Dev Biol. 1998 Jun;9(3):279-84. doi: 10.1006/scdb.1998.0233.
The vertebrate retina is an extraordinary example of the modular design of the nervous tissue. Retinal neurons are organized in layers and, within each layer, cells of the same type commonly form orderly planar arrays - the retinal mosaics - which provide the basis for powerful parallel processing of the visual scene. Recent evidence indicates that the assembly of neuronal mosaics is an early event in retinal development, a finding with important implications for the control of genesis, fate determination, migration and death of developing retinal neurons.
脊椎动物的视网膜是神经组织模块化设计的一个非凡例证。视网膜神经元分层排列,并且在每一层内,相同类型的细胞通常形成有序的平面阵列——视网膜镶嵌,这为视觉场景的强大并行处理提供了基础。最近的证据表明,神经元镶嵌的组装是视网膜发育中的一个早期事件,这一发现对于发育中的视网膜神经元的发生、命运决定、迁移和死亡的控制具有重要意义。