Kowalewski K
Lab Anim Sci. 1976 Aug;26(4):562-5.
The effect of age and sex on histamine-stimulated 24-hr gastric secretion was assessed in the rat. Secretion tests were done in rats of both sexes at 3, 6, 9, 12, 18, and 24 mo of age. The highest 24-hr volume and acid output of gastric secretion was found in both sexes in the 9-mo age group. When related to body weight the highest 24-hr gastric secretion and acid output was found in 6-mo-old males and in 9-mo-old females. This observation may have practical value when the rat is selected as an experimental tool for the study of gastric secretory function.
评估了年龄和性别对组胺刺激的大鼠24小时胃分泌的影响。对3、6、9、12、18和24月龄的雌雄大鼠均进行了分泌测试。在9月龄组的雌雄大鼠中均发现24小时胃分泌量和酸排出量最高。与体重相关时，6月龄雄性大鼠和9月龄雌性大鼠的24小时胃分泌量和酸排出量最高。当选择大鼠作为研究胃分泌功能的实验工具时，这一观察结果可能具有实际价值。
