Di Palma A, Vullo C, Zani B, Facchini A
Pediatric Department, S. Anna Hospital, Ferrara, Italy.
Ann N Y Acad Sci. 1998 Jun 30;850:355-60. doi: 10.1111/j.1749-6632.1998.tb10493.x.
The aim of this study was to explore the effect of thalassemia major on the psychosocial adjustment of adolescents and young adults.
unmarried adolescent and young adult patients were asked to fill in an ad hoc questionnaire; a semi-structured interview exploring marriage and family life was done with married patients.
group A: 90 unmarried patients, 50% females and 50% males, aged 14-22 years. The control group was formed by 100 matched subjects; group B: 19 thalassemic married subjects, 6 males and 13 females, aged 28-45 years, 7 patients had children and 12 did not.
group A: subjects with thalassemia had normal psychological and social development and scored better than their normal peers in tests investigating social adjustment, self-esteem and self-description. Moreover the family relationships of adolescents with thalassemia appeared to be stronger than those reported by normal controls; group B: the behavior of thalassemic couples did not differ from the one observed in non-thalassemic couples in the course of previous investigations.
Our data shows that neither thalassemic adolescents nor thalassemic married, well-treated, young adults differ significantly from the healthy young people in their ability to cope with life's difficulties both in adolescence and marital life.
本研究的目的是探讨重型地中海贫血对青少年和青年心理社会适应的影响。
要求未婚青少年和青年患者填写一份特制问卷；对已婚患者进行了一次探索婚姻和家庭生活的半结构化访谈。
A组：90名未婚患者，男女各占50%，年龄在14至22岁之间。对照组由100名匹配对象组成；B组：19名地中海贫血已婚患者，6名男性和13名女性，年龄在28至45岁之间，7名患者有子女，12名没有。
A组：地中海贫血患者心理和社会发展正常，在调查社会适应、自尊和自我描述的测试中得分高于正常同龄人。此外，地中海贫血青少年的家庭关系似乎比正常对照组报告的更强；B组：地中海贫血夫妇的行为与之前调查中观察到的非地中海贫血夫妇的行为没有差异。
我们的数据表明，无论是地中海贫血青少年还是已婚、治疗良好的地中海贫血青年，在应对青春期和婚姻生活中的生活困难方面，与健康年轻人相比均无显著差异。
