Henderson R D, Woolf C, Marryatt G
Laryngoscope. 1976 Oct;86(10):1531-9. doi: 10.1288/00005537-197610000-00007.
Pharyngoesophageal dysphagia occurred in 51.3 percent of 1,000 consecutive patients with gastroesophageal reflux. Aspiration, secondary to food obstruction, occurred in 30 percent of these patients, and some developed significant secondary respiratory symptoms. The site of obstruction was localized to the cricopharyngeus by timing the interval from swallow to obstruction. Cricopharyngeal incoordination was demonstrated in 20 of 52 patients studied by high speed esophageal manometry. Surgical correction of gastroesophageal reflux in patients with intractable reflux symptoms was shown to be effective in relieving pharyngoesophageal dysphagia in all but a small number of patients with very severe symptoms. In those with persistent dysphagia cricopharyngeal myotomy at a later stage was effective in giving relief.
在连续的1000例胃食管反流患者中，51.3%出现咽食管吞咽困难。这些患者中有30%因食物梗阻继发误吸，部分患者出现明显的继发呼吸道症状。通过计算吞咽至梗阻的时间间隔，梗阻部位定位于环咽肌。在52例接受高速食管测压研究的患者中，20例显示环咽肌不协调。对于有顽固性反流症状的患者，手术纠正胃食管反流被证明除少数症状非常严重的患者外，对缓解咽食管吞咽困难有效。对于持续吞咽困难的患者，后期行环咽肌切开术有效缓解症状。
