Holm T, Kildahl-Andersen O, Valle P C
Medical Dept. B, Rikshospitalet, Oslo, Norway.
Scand J Gastroenterol. 1998 Jun;33(6):669-72. doi: 10.1080/00365529850171972.
A 39-year-old man presenting with pulmonary infiltrations and hemolytic anemia was diagnosed as having primary sclerosing cholangitis (PSC) without evidence of ulcerative colitis. This constellation of associations is unique to the best of our knowledge. Autoimmune hemolytic anemia has been reported to be associated with PSC on only a few occasions, and pulmonary infiltrations in association with PSC are also quite unusual. Genetic and immunologic mechanisms are major factors in the pathogenesis of these disorders.
一名39岁男性，出现肺部浸润和溶血性贫血，被诊断为原发性硬化性胆管炎（PSC），无溃疡性结肠炎证据。据我们所知，这种关联组合是独一无二的。自身免疫性溶血性贫血仅有少数几次被报道与PSC相关，而与PSC相关的肺部浸润也相当罕见。遗传和免疫机制是这些疾病发病机制中的主要因素。
