Ferrari A, Gaia E, Cavallero M
Minerva Med. 1976 Sep 19;67(43):2819-22.
On the basis of some experimental observations of hypergastrinemia in animals chronically intoxicated with ethanol, both fasting and after meals serum gastrin were determined in patients affected by chronic alcoholic pancreatitis. A significant increase in serum gastrin levels was observed in patients with chronic pancreatitis compared with controls, both in basal conditions and following food stimulation. The physiopathological hypotheses and possible aetiopathogenetic implications suggested by such gastrin behaviour are discussed.
基于对长期乙醇中毒动物高胃泌素血症的一些实验观察,对慢性酒精性胰腺炎患者测定了空腹和餐后血清胃泌素水平。与对照组相比,慢性胰腺炎患者在基础状态和食物刺激后血清胃泌素水平均显著升高。本文讨论了这种胃泌素行为所提示的生理病理假说及可能的病因学意义。