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在慢性钙化性胰腺炎和慢性酒精中毒中胃泌素释放增加。

Increased gastrin release in chronic calcifying pancreatitis and in chronic alcoholism.

作者信息

Treffot M J, Laugier R, Bretholz A, Voirol M, Sarles H

出版信息

Horm Metab Res. 1980;12(6):240-2. doi: 10.1055/s-2007-996257.

DOI:10.1055/s-2007-996257
PMID:7409735
Abstract

Plasma gastrin levels were measured by radioimmunoassay before and after a test meal associated with 40 ml ethanol in 21 patients presenting with chronic calcifying pancreatitis, in 10 apparently normal subjects drinking since at least 5 years 100 g alcohol a day, in 14 subjects presenting hepatic alcoholic cirrhosis and in 18 apparently normal non alcoholic controls. Post-stimulation gastrin concentration were higher in chronic pancreatitis patients or in normal alcoholics (peak post-stimulation value: 74 +/- 41 and 74 +/- 43 pg/ml respectively) than in cirrhotics or non alcoholic controls (45 +/- 26 and 41 +/- 15 pg/ml respectively) (m +/- SD).

摘要

采用放射免疫分析法测定了21例慢性钙化性胰腺炎患者、10例每天饮用100克酒精至少5年的明显正常受试者、14例酒精性肝硬化患者和18例明显正常的非酒精对照者在摄入含40毫升乙醇的试验餐前后的血浆胃泌素水平。慢性胰腺炎患者或正常酗酒者(刺激后峰值分别为:74±41和74±43皮克/毫升)刺激后胃泌素浓度高于肝硬化患者或非酒精对照者(分别为45±26和41±15皮克/毫升)(均值±标准差)。

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Horm Metab Res. 1980;12(6):240-2. doi: 10.1055/s-2007-996257.
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